Bounding the FDP in competition-based control of the FDR
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Publication:57837
DOI10.48550/ARXIV.2302.11837arXiv2302.11837MaRDI QIDQ57837FDOQ57837
Uri Keich, Jack Freestone, Arya Ebadi, Dong Luo, William Stafford Noble
Publication date: 23 February 2023
Abstract: Competition-based approach to controlling the false discovery rate (FDR) recently rose to prominence when, generalizing it to sequential hypothesis testing, Barber and Cand`es used it as part of their knockoff-filter. Control of the FDR implies that the, arguably more important, false discovery proportion is only controlled in an average sense. We present TDC-SB and TDC-UB that provide upper prediction bounds on the FDP in the list of discoveries generated when controlling the FDR using competition. Using simulated and real data we show that, overall, our new procedures offer significantly tighter upper bounds than ones obtained using the recently published approach of Katsevich and Ramdas, even when the latter is further improved using the interpolation concept of Goeman et al.
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