A Minimax Optimal Ridge-Type Set Test for Global Hypothesis With Applications in Whole Genome Sequencing Association Studies

DOI10.1080/01621459.2020.1831926OpenAlexW3092466230MaRDI QIDQ5885114

Xihong Lin, Zilin Li, Yao-Wu Liu

Publication date: 27 March 2023

Published in: Journal of the American Statistical Association (Search for Journal in Brave)

Full work available at URL: https://doi.org/10.1080/01621459.2020.1831926

zbMATH Keywords

score test\(F\)-testsignal strengthglobal hypothesis testingrobust powerwhole genome sequencing studies

Mathematics Subject Classification ID

Computational methods for problems pertaining to statistics (62-08) Applications of statistics to biology and medical sciences; meta analysis (62P10) Minimax procedures in statistical decision theory (62C20)

Cites Work

• Unnamed Item
• Testing against a high-dimensional alternative in the generalized linear model: asymptotic type I error control
• A new chi-square approximation to the distribution of non-negative definite quadratic forms in non-central normal variables
• Cauchy Combination Test: A Powerful Test With Analytic p-Value Calculation Under Arbitrary Dependency Structures
• Testing Against a High Dimensional Alternative
• Algorithm AS 155: The Distribution of a Linear Combination of χ 2 Random Variables
• Variance component testing in generalised linear models with random effects
• Miscellanea. Saddlepoint approximations for distributions of quadratic forms in normal variables
• Genetic Variant Set-Based Tests Using the Generalized Berk–Jones Statistic With Application to a Genome-Wide Association Study of Breast Cancer