DICE: A Bayesian model for early dose finding in phase I trials with multiple treatment courses

DOI10.1002/bimj.202000369zbMath1523.62223OpenAlexW3208368031MaRDI QIDQ6068878

Moreno Ursino, Unnamed Author, Sylvie Chevret

Publication date: 15 December 2023

Published in: Biometrical Journal (Search for Journal in Brave)

Full work available at URL: https://doi.org/10.1002/bimj.202000369

zbMATH Keywords

Bayesian modeloncologycumulative toxicitydose finding design

Mathematics Subject Classification ID

Applications of statistics to biology and medical sciences; meta analysis (62P10)

Cites Work

• Continual Reassessment Method: A Practical Design for Phase 1 Clinical Trials in Cancer
• A Phase I Bayesian Adaptive Design to Simultaneously Optimize Dose and Schedule Assignments Both Between and Within Patients
• Determining the Effective Sample Size of a Parametric Prior
• Sequential Designs for Phase I Clinical Trials with Late‐Onset Toxicities
• Determining a Maximum‐Tolerated Schedule of a Cytotoxic Agent

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