A study on the transmission dynamics of COVID-19 considering the impact of asymptomatic infection

DOI10.1080/17513758.2023.2244980zbMATH Open1521.92097arXiv2210.13114OpenAlexW4386356679MaRDI QIDQ6074046FDOQ6074046

Zonghao Zhang, Maoxing Liu, Xiaojing Wang, Xiaotong Huang, Author name not available (Why is that?), Songbai Guo, Chuanqing Xu, Xiaoling Liu

Publication date: 18 September 2023

Published in: Journal of Biological Dynamics (Search for Journal in Brave)

Abstract: The COVID-19 epidemic has been spreading around the world for nearly three years, and asymptomatic infections have exacerbated the spread of the epidemic. To evaluate the role of asymptomatic infections in the spread of the epidemic, we develop mathematical models to assess the proportion of asymptomatic infections caused by different strains of the main covid-19 variants. The analysis shows that when the control reproduction number is less than 1, the disease-free equilibrium point of the model is globally asymptotically stable; and when the control reproduction number is greater than 1, the endemic equilibrium point exists and is unique, and is locally asymptotically stable. We fit the epidemic data in the four time periods corresponding to the selected 614G, Alpha, Delta and Omicron variants. The fitting results show that, from the comparison of the four time periods, the proportion of asymptomatic persons among the infected persons gradually increased. We also predict the peak time and peak value for the four time periods, and the results indicate that the transmission speed and transmission intensity of the variant strains increased to some extent. Finally, we discuss the impact of the detection ratio of symptomatic infections on the spread of the epidemic. The results show that with the increase of the detection ratio, the cumulative number of cases has dropped significantly, but the decline in the proportion of asymptomatic infections is not obvious. Therefore, in view of the hidden transmission of asymptomatic infections, the cooperation between various epidemic prevention and control policies is required to effectively curb the spread of the epidemic.

Full work available at URL: https://arxiv.org/abs/2210.13114

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zbMATH Keywords

COVID-19Lyapunov functiondata fittingcontrol reproduction numberasymptomatic infections

Mathematics Subject Classification ID

Epidemiology (92D30) Stability of solutions to ordinary differential equations (34D20)

Cites Work

• Modeling the dynamic of COVID-19 with different types of transmissions
• Analysis of HIV models with two time delays
• Effect of delay in diagnosis on transmission of COVID-19
• Global stability of a mumps transmission model with quarantine measure

Cited In (4)

• Modelling the impact of repeat asymptomatic testing policies for staff on SARS-CoV-2 transmission potential
• A multi-strain model with asymptomatic transmission: application to COVID-19 in the US
• Modelling and simulating the novel coronavirus with implications of asymptomatic carriers
• The Role of Asymptomatic Infections in the COVID-19 Epidemic via Complex Networks and Stability Analysis

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