Causal Inference in Transcriptome-Wide Association Studies with Invalid Instruments and GWAS Summary Data

DOI10.1080/01621459.2023.2183127MaRDI QIDQ6077539zbMATH OpenOpenAlexWikidataFDO

Authors Xiaotong Shen, Wei Pan

Publication date 18 October 2023

Published in Journal of the American Statistical Association (Search for Journal in Brave)

Full work available at URL https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10557939

zbMATH Keywords

2SLScausal inferencegenome-wide association studiesMendelian randomization (MR)reference panelSNPtruncated \(L_1\)-constraint (TLC)

Mathematics Subject Classification ID

Statistics (62-XX)

Cites work

• A symmetric matrix-variate normal local approximation for the Wishart distribution and some applications
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• Robust inference for the two-sample 2SLS estimator
• Statistical inference in two-sample summary-data Mendelian randomization using robust adjusted profile score
• Weak‐instrument robust tests in two‐sample summary‐data Mendelian randomization

Cited in

(2)

• A modification to two-stage least squares with genetic applications
• High-dimensional statistical inference for linkage disequilibrium score regression and its cross-ancestry extensions

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