A phase-field system arising from multiscale modeling of thrombus biomechanics in blood vessels: local well-posedness in dimension two

DOI10.3934/DCDSS.2023105MaRDI QIDQ6089457zbMATH OpenOpenAlexFDO

Authors Maurizio Grasselli, Andrea Poiatti

Publication date 17 November 2023

Published in Discrete and Continuous Dynamical Systems. Series S (Search for Journal in Brave)

Full work available at URL https://arxiv.org/abs/2304.03364

zbMATH Keywords

Cahn-Hilliard equationexistence and uniquenessFlory-Huggins potentiallocal strong solutionsNavier-Stokes systemtransport equation

Mathematics Subject Classification ID

Existence problems for PDEs: global existence, local existence, non-existence (35A01) Uniqueness problems for PDEs: global uniqueness, local uniqueness, non-uniqueness (35A02) Smoothness and regularity of solutions to PDEs (35B65) Strong solutions to PDEs (35D35) Initial-boundary value problems for nonlinear higher-order PDEs (35G31) PDEs in connection with fluid mechanics (35Q35) Transport equations (35Q49) PDEs in connection with biology, chemistry and other natural sciences (35Q92) Existence, uniqueness, and regularity theory for incompressible viscous fluids (76D03) Navier-Stokes equations for incompressible viscous fluids (76D05) Physiological flows (76Z05) Physiological flow (92C35)

Abstract: We consider a phase-field model which describes the interactions between the blood flow and the thrombus. The latter is supposed to be a viscoelastic material. The potential describing the cohesive energy of the mixture is assumed to be of Flory-Huggins type (i.e. logarithmic). This ensures the boundedness from below of the dissipation energy. In the two dimensional case, we prove the local (in time) existence and uniqueness of a strong solution, provided that the two viscosities of the pure fluid phases are close enough. We also show that the order parameter remains strictly separated from the pure phases if it is so at the initial time.

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Cited in

(1)

• On the well-posedness of the Cahn-Hilliard-Biot model and its applications to tumor growth

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