Stochastic simulation uncertainty analysis to accelerate flexible biomanufacturing process development

DOI10.1016/j.ejor.2023.01.055arXiv2203.08980OpenAlexW4221163271MaRDI QIDQ6113323

Ke-Qi Wang, Wei Xie, Barry L. Nelson, Russell R. Barton

Publication date: 11 July 2023

Published in: European Journal of Operational Research (Search for Journal in Brave)

Full work available at URL: https://arxiv.org/abs/2203.08980

zbMATH Keywords

uncertainty quantification (UQ)sensitivity analysis (SA)Gaussian process (GP)biomanufacturing systemshybrid simulation model

Mathematics Subject Classification ID

Operations research and management science (90Bxx)

Cites Work

• Sensitivity analysis: a review of recent advances
• The design and analysis of computer experiments.
• Regression and Kriging metamodels with their experimental designs in simulation: a review
• Quantifying Input Uncertainty via Simulation Confidence Intervals
• Stochastic Kriging for Simulation Metamodeling
• Accounting for Parameter Uncertainty in Large-Scale Stochastic Simulations with Correlated Inputs
• Shapley Effects for Global Sensitivity Analysis: Theory and Computation
• Performance Guarantees and Optimal Purification Decisions for Engineered Proteins
• Subsampling to Enhance Efficiency in Input Uncertainty Quantification
• Interpretable biomanufacturing process risk and sensitivity analyses for quality‐by‐design and stability control
• A Factor-Based Bayesian Framework for Risk Analysis in Stochastic Simulations

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