Tracking hematopoietic stem cell evolution in a Wiskott-Aldrich clinical trial

DOI10.1214/22-aoas1686OpenAlexW4386511765MaRDI QIDQ6138475

Luca Biasco, Clelia Di Serio, Danilo Pellin, Ernst C. Wit, Serena Scala

Publication date: 16 January 2024

Published in: The Annals of Applied Statistics (Search for Journal in Brave)

Full work available at URL: https://doi.org/10.1214/22-aoas1686

zbMATH Keywords

nonlinear differential equationsmaster equationgene therapyclonal trackinggeneralized method-of-momentsmultivariate Markov processWiskott-Aldrich syndrome

Mathematics Subject Classification ID

Applications of statistics (62Pxx)

Cites Work

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• Statistical inference for partially observed branching processes with application to cell lineage tracking of \textit{in vivo} hematopoiesis
• A derivative matching approach to moment closure for the stochastic logistic model
• An extension of the moment closure method
• Approximation and inference methods for stochastic biochemical kinetics—a tutorial review
• Bayesian Inference for Stochastic Kinetic Models Using a Diffusion Approximation

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