Time‐optimal control of piecewise affine bistable gene‐regulatory networks

DOI10.1002/RNC.6012OpenAlexW4210544069MaRDI QIDQ6152809FDOQ6152809

Authors: Nicolas Augier, Agustín Gabriel Yabo 

Publication date: 13 February 2024

Published in: International Journal of Robust and Nonlinear Control (Search for Journal in Brave)

Full work available at URL: https://doi.org/10.1002/rnc.6012

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zbMATH Keywords

biological systemshybrid systemsbistable switchgenetic toggle switchhybrid optimal controlgenetic regulatory systems

Mathematics Subject Classification ID

Genetics and epigenetics (92D10) Systems biology, networks (92C42) Optimality conditions for solutions belonging to restricted classes (Lipschitz controls, bang-bang controls, etc.) (49K30) Attainable sets, reachability (93B03)

Cites Work

• The turnpike property in finite-dimensional nonlinear optimal control
• Title not available (Why is that?)
• The Poincaré-Bendixson theorem for monotone cyclic feedback systems
• The hybrid maximum principle is a consequence of Pontryagin's maximum principle
• Exact control of genetic networks in a qualitative framework: the bistable switch example
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• Time minimal trajectories for a spin 1∕2 particle in a magnetic field
• Minimal time trajectories for two-level quantum systems with two bounded controls
• A passivity-based stability criterion for a class of biochemical reaction networks
• Passivity gains and the ``secant condition for stability
• Optimal control of bacterial growth for the maximization of metabolite production
• Optimal bacterial resource allocation: metabolite production in continuous bioreactors
• Qualitative control of undesired oscillations in a genetic negative feedback loop with uncertain measurements

Cited In (1)

• Random periodic sequence of globally mean-square exponentially stable discrete-time stochastic genetic regulatory networks with discrete spatial diffusions

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