A mathematical model for intracellular NO and ROS dynamics in vascular endothelial cells activated by exercise-induced wall shear stress

DOI10.1016/J.MBS.2023.109009MaRDI QIDQ6167796zbMATH OpenOpenAlexFDO

Authors Xiao Zeng, Chundong Xue, Yongjiang Li, Kai-Rong Qin

Publication date 7 August 2023

Published in Mathematical Biosciences (Search for Journal in Brave)

Full work available at URL https://doi.org/10.1016/j.mbs.2023.109009

zbMATH Keywords

dynamic modelendothelial cellsnitric oxidereactive oxygen specieswall shear stress

Mathematics Subject Classification ID

Physiological flow (92C35) Cell biology (92C37)

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Cites work

• A mathematical model for ATP-mediated calcium dynamics in vascular endothelial cells induced by fluid shear stress
• Metabotropic receptor activation, desensitization and sequestration. I: Modelling calcium and inositol 1,4,5-trisphosphate dynamics following receptor activation

Cited in

(5)

• A mathematical model for ATP-mediated calcium dynamics in vascular endothelial cells induced by fluid shear stress
• Mathematical modeling of ischemia-reperfusion injury and postconditioning therapy
• A mathematical model of endothelial nitric oxide synthase activation with time delay exhibiting Hopf bifurcation and oscillations
• Dynamics of calcium signal and leukotriene \(\mathrm{C}_4\) release in mast cells network induced by mechanical stimuli and modulated by interstitial fluid flow
• Unveiling the negative synergistic effect of wall shear stress and insulin on endothelial NO dynamics by mathematical modeling

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