Space-time Multilevel Quadrature Methods and their Application for Cardiac Electrophysiology

DOI10.1137/21M1418320arXiv2105.02007OpenAlexW3159186831MaRDI QIDQ6188697FDOQ6188697

Authors: H. Harbrecht, Rolf Krause, Michael Peters, A. Quaglino, Marc Schmidlin 

Publication date: 11 January 2024

Published in: SIAM/ASA Journal on Uncertainty Quantification (Search for Journal in Brave)

Abstract: We present a novel approach which aims at high-performance uncertainty quantification for cardiac electrophysiology simulations. Employing the monodomain equation to model the transmembrane potential inside the cardiac cells, we evaluate the effect of spatially correlated perturbations of the heart fibers on the statistics of the resulting quantities of interest. Our methodology relies on a close integration of multilevel quadrature methods, parallel iterative solvers and space-time finite element discretizations, allowing for a fully parallelized framework in space, time and stochastics. Extensive numerical studies are presented to evaluate convergence rates and to compare the performance of classical Monte Carlo methods such as standard Monte Carlo (MC) and quasi-Monte Carlo (QMC), as well as multilevel strategies, i.e. multilevel Monte Carlo (MLMC) and multilevel quasi-Monte Carlo (MLQMC) on hierarchies of nested meshes. Finally, we employ a recently suggested variant of the multilevel approach for non-nested meshes to deal with a realistic heart geometry.

Full work available at URL: https://arxiv.org/abs/2105.02007

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zbMATH Keywords

space-time methodsmultilevel methodsmonodomain equationcardiac electrophysiologyheart fibers uncertainty

Mathematics Subject Classification ID

Stochastic partial differential equations (aspects of stochastic analysis) (60H15) Stochastic integrals (60H05) Computational methods for stochastic equations (aspects of stochastic analysis) (60H35) Probabilistic methods, stochastic differential equations (65Cxx) Computational methods for problems pertaining to measure and integration (28-08)

Cites Work

• On the low-rank approximation by the pivoted Cholesky decomposition
• Multilevel Monte Carlo Path Simulation
• Title not available (Why is that?)
• Multi-level Monte Carlo finite element method for elliptic PDEs with stochastic coefficients
• A note on the construction of \(L\)-fold sparse tensor product spaces
• 50 years of time parallel time integration
• Approximation theory in tensor product spaces
• Efficient approximation of random fields for numerical applications.
• Qualitative theory of the Fitz Hugh-Nagumo equations
• Gradient flows and variational principles for cardiac electrophysiology: toward efficient and robust numerical simulations of the electrical activity of the heart
• A simple proposal for parallel computation over time of an evolutionary process with implicit time stepping
• Title not available (Why is that?)
• Decoupled time-marching schemes in computational cardiac electrophysiology and ECG numerical simulation
• Title not available (Why is that?)
• Multilevel Quasi-Monte Carlo Uncertainty Quantification for Advection-Diffusion-Reaction
• Uncertainty quantification for PDEs with anisotropic random diffusion
• Space-Time FE-DG Discretization of the Anisotropic Diffusion Equation in Any Dimension: The Spectral Symbol
• Scheduling massively parallel multigrid for multilevel Monte Carlo methods
• Multilevel methods for uncertainty quantification of elliptic PDEs with random anisotropic diffusion
• Multilevel quadrature for elliptic parametric partial differential equations in case of polygonal approximations of curved domains
• Space-time multilevel Monte Carlo methods and their application to cardiac electrophysiology

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