Optimal designs for discriminating between dose-response models in toxicology studies

DOI10.3150/10-BEJ257zbMath1207.62154arXiv1011.5747OpenAlexW3104333438MaRDI QIDQ627292

Weng Kee Wong, Andrey Pepelyshev, Piter Shpilev, Dette, Holger

Publication date: 28 February 2011

Published in: Bernoulli (Search for Journal in Brave)

Full work available at URL: https://arxiv.org/abs/1011.5747

zbMATH Keywords

robust designcontinuous designmodel discriminationlocally optimal designmaximin optimal design

Mathematics Subject Classification ID

Applications of statistics to biology and medical sciences; meta analysis (62P10) Optimal statistical designs (62K05) General nonlinear regression (62J02) Robust parameter designs (62K25)

Related Items (4)

Optimum Experimental Designs for Choosing Between Competitive and Non Competitive Models of Enzyme Inhibition ⋮ Maximin designs for the detection of synergistic effects ⋮ An equivalence theorem for design optimality with respect to a multi-objective criterion ⋮ Design issues related to allocation of experimental units with known covariates into two treatment groups

Cites Work

• Unnamed Item
• Unnamed Item
• Unnamed Item
• Unnamed Item
• A generalization of D- and \(D_ 1\)-optimal designs in polynomial regression
• Optimal weights for experimental designs on linearly independent support points
• Optimal designs for discriminating between some extensions of the Michaelis-Menten model
• General equivalence theory for optimum designs (approximate theory)
• Discrimination designs for polynomial regression on compact intervals
• Maximin efficient designs for estimating nonlinear aspects in linear models
• Optimal discrimination designs for multifactor experiments
• Optimal designs for the identification of the order of a Fourier regression
• Optimal designs for identifying the degree of a polynomial regression
• Optimal discrimination designs
• Asymptotic Statistics
• An Optimal Experimental Design Criterion for Discriminating Between Non-Normal Models
• Asymptotic Properties of Non-Linear Least Squares Estimators
• Optimal Design for Goodness-of-Fit of the Michaelis–Menten Enzyme Kinetic Function
• Locally Optimal Designs for Estimating Parameters

This page was built for publication: Optimal designs for discriminating between dose-response models in toxicology studies