Characterisation of Optimal Responses to Pulse Inputs in the Bergman Minimal Model
From MaRDI portal
Publication:6284096
arXiv1703.03134MaRDI QIDQ6284096FDOQ6284096
Authors: Christopher F. Townsend, María M. Seron, Graham C. Goodwin 
Publication date: 9 March 2017
Abstract: The Bergman minimal model is a dynamic model of plasma glucose concentration. It has two input variables -- insulin delivery and carbohydrate intake. We investigate the behaviour of plasma glucose concentration predicted by the model given carbohydrate (CHO) inputs and commensurate insulin inputs. We observe that to maintain plasma glucose above a specified minimum concentration results in an unavoidable peak in plasma glucose. Additionally, we specify the timing and magnitude of a bolus pulse to minimise this unavoidable peak in plasma glucose concentration whilst attaining but not going below the desired minimum glucose concentration. Finally, we obtain necessary and sufficient conditions for the glucose concentration to be minimised.
This page was built for publication: Characterisation of Optimal Responses to Pulse Inputs in the Bergman Minimal Model
Report a bug (only for logged in users!)Click here to report a bug for this page (MaRDI item Q6284096)
