Existence of Global Classical and Weak Solutions to a Prion Equation with Polymer Joining
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Publication:6284755
DOI10.1007/S00028-016-0379-6arXiv1703.08331MaRDI QIDQ6284755FDOQ6284755
Authors: Elena Leis, Christoph Walker 
Publication date: 24 March 2017
Abstract: We consider a nonlinear integro-differential equation for prion proliferation that includes prion polymerization, polymer splitting, and polymer joining. The equation can be written as a quasilinear Cauchy problem. For bounded reaction rates we prove global existence and uniqueness of classical solutions by means of evolution operator theory. We also prove global existence of weak solutions for unbounded reaction rates by a compactness argument.
PDEs in connection with biology, chemistry and other natural sciences (35Q92) Integro-partial differential equations (35R09)
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