Asymptotic preserving P_N methods for haptotaxis equations

Publication date 18 September 2019

Population dynamics (general) (92D25) PDEs in connection with biology, chemistry and other natural sciences (35Q92) Finite volume methods for initial value and initial-boundary value problems involving PDEs (65M08) Stability and convergence of numerical methods for initial value and initial-boundary value problems involving PDEs (65M12) Method of lines for initial value and initial-boundary value problems involving PDEs (65M20) Cell movement (chemotaxis, etc.) (92C17) Initial-boundary value problems for first-order hyperbolic equations (35L04) Spectral, collocation and related methods for initial value and initial-boundary value problems involving PDEs (65M70)

Abstract: The so-called haptotaxis equation is a special class of transport equation that arises from models of biological cell movement along tissue fibers. This equation has an anisotropic advection-diffusion equation as its macroscopic limit. An up to second-order accurate asymptotic preserving method is developed for the haptotaxis equation in space dimension up to three. For this the micro-macro decomposition proposed by Lemou and Mieussens is generalized in the context of finite-volume schemes on staggered grids. The spurious modes that arise from this discretization can be eliminated by combining flux evaluations from different points in the right way. The velocity space is discretized by an arbitrary-order linear moment system (

P_{N}

).

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