Homeostasis and injectivity: a reaction network perspective
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Publication:6366554
DOI10.1007/S00285-022-01795-3arXiv2105.00088WikidataQ123337823 ScholiaQ123337823MaRDI QIDQ6366554FDOQ6366554
Abhishek Deshpande, Gheorghe Craciun
Publication date: 30 April 2021
Abstract: Homeostasis is a mechanism by which a feature can remain invariant with change in external parameters. We adopt the definition of homeostasis in the context of singularity theory. We make a connection between homeostasis and the theory of injective reaction networks. In particular, we show that a reaction network cannot exhibit homeostasis if a modified reaction network (which we call the homeostasis-associated reaction network) is injective. We provide examples of reaction networks which can or cannot exhibit homeostasis by analyzing the injectivity of the homeostasis-associated reaction network.
Dynamical systems in biology (37N25) Toric varieties, Newton polyhedra, Okounkov bodies (14M25) General biology and biomathematics (92B05) Kinetics in biochemical problems (pharmacokinetics, enzyme kinetics, etc.) (92C45) Chemical kinetics in thermodynamics and heat transfer (80A30) Classical flows, reactions, etc. in chemistry (92E20)
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