On the sodium concentration diffusion with three-dimensional extracellular stimulation

DOI10.1155/2011/862813MaRDI QIDQ638092zbMATH OpenOpenAlexWikidataFDO

Authors Luisa Consiglieri, Ana Rute Domingos

Publication date 9 September 2011

Published in International Journal of Mathematics and Mathematical Sciences (Search for Journal in Brave)

Copyright license Creative Commons Attribution 4.0 International

Full work available at URL https://doi.org/10.1155/2011/862813

Mathematics Subject Classification ID

PDEs in connection with biology, chemistry and other natural sciences (35Q92) Neural biology (92C20) Cell biology (92C37)

Review text

Summary: We deal with transmembrane sodium diffusion in a nerve. We study a mathematical model of a nerve fibre in response to an imposed extracellular stimulus. The presented model is constituted by a diffusion-drift vectorial equation in a bidomain, that is, two parabolic equations defined in each of the intra- and extra-regions. This system of partial differential equations can be understood as a reduced three-dimensional Poisson-Nernst-Planck model of the sodium concentration. The representation of the membrane includes a jump boundary condition describing the mechanisms involved in the excitation-contraction couple. Our first novelty comes from this general dynamical boundary condition. The second one is the three-dimensional behaviour of the extracellular stimulus. An analytical solution to the mathematical model is proposed depending on the morphology of the excitation.

Recommendations

• A cell-based model for ionic electrodiffusion in excitable tissue
• Effect of intracellular diffusion on current-voltage curves in potassium channels
• Effects of maximal sodium and potassium conductance on the stability of Hodgkin-Huxley model
• Geometrical effects on nonlinear electrodiffusion in cell physiology
• Electrodiffusion of ions inside living cells
• Electrodiffusion models of axon and extracellular space using the Poisson-Nernst-Planck equations
• Electrodiffusion Model of Rectangular Current Pulses in Ionic Channels of Cellular Membranes
• A 3D reaction-diffusion system describing calcium dynamics in cardiac cell
• Electrodiffusion near an ion channel and the effect of mobile buffer

Cites work

• Chaos in the Hodgkin--Huxley Model
• Exponential asymptotic stability for an elliptic equation with memory arising in electrical conduction in biological tissues
• Giant squid-hidden canard: the 3D geometry of the Hodgkin-Huxley model
• scientific article; zbMATH DE number 5864685 (Why is no real title available?)
• scientific article; zbMATH DE number 1443574 (Why is no real title available?)
• scientific article; zbMATH DE number 3273551 (Why is no real title available?)
• scientific article; zbMATH DE number 3082267 (Why is no real title available?)
• Identifying generalized Fitzhugh-Nagumo equation from a numerical solution of Hodgkin-Huxley model
• Poisson-Nernst-Planck equations for simulating biomolecular diffusion-reaction processes. I: Finite element solutions
• Poisson–Nernst–Planck Systems for Ion Channels with Permanent Charges
• Reduction of presynaptic action potentials by PAD: Model and experimental study
• Trust Management
• Uniqueness of steady-state solutions for an electrochemistry model with multiple species

Cited in

(3)

• A new 3D mass diffusion-reaction model in the neuromuscular junction
• Electrodiffusion models of axon and extracellular space using the Poisson-Nernst-Planck equations
• scientific article; zbMATH DE number 5262810 (Why is no real title available?)

This page was built for publication: On the sodium concentration diffusion with three-dimensional extracellular stimulation

Report a bug (only for logged in users!)Click here to report a bug for this page (MaRDI item Q638092)