Analysis of a Poisson-Nernst-Planck-Fermi system for charge transport in ion channels

DOI10.1016/J.JDE.2024.02.046MaRDI QIDQ6437841zbMATH OpenOpenAlexFDO

Authors Ansgar Jüngel, Annamaria Massimini

Publication date 24 May 2023

Full work available at URL https://doi.org/10.1016/j.jde.2024.02.046

Mathematics Subject Classification ID

Boundary value problems for higher-order elliptic equations (35J40) Initial-boundary value problems for second-order parabolic systems (35K51) PDEs in connection with biology, chemistry and other natural sciences (35Q92) Cell biology (92C37)

Abstract: A modified Poisson-Nernst-Planck system in a bounded domain with mixed Dirichlet-Neumann boundary conditions is analyzed. It describes the concentrations of ions immersed in a polar solvent and the correlated electric potential due to the ion--solvent interaction. The concentrations solve cross-diffusion equations, which are thermodynamically consistent. The considered mixture is saturated, meaning that the sum of the ion and solvent concentrations is constant. The correlated electric potential depends nonlocally on the electric potential and solves the fourth-order Poisson-Fermi equation. The existence of global bounded weak solutions is proved by using the boundedness-by-entropy method. The novelty of the paper is the proof of the weak--strong uniqueness property. In contrast to the existence proof, we include the solvent concentration in the cross-diffusion system, leading to a diffusion matrix with nontrivial kernel. Then the proof is based on the relative entropy method for the extended cross-diffusion system and the positive definiteness of a related diffusion matrix on a subspace.

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Cited in

(1)

• Weak-strong uniqueness for general cross-diffusion systems with volume filling

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