Effective interface conditions for a porous medium type problem
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Publication:6507571
DOI10.4171/IFB/505arXiv2105.02063MaRDI QIDQ6507571FDOQ6507571
Authors: Giorgia Ciavolella, Noemi David, Alexandre Poulain 
Abstract: Motivated by biological applications on tumour invasion through thin membranes, we study a porous-medium type equation where the density of the cell population evolves under Darcy's law, assuming continuity of both the density and flux velocity on the thin membrane which separates two domains. The drastically different scales and mobility rates between the membrane and the adjacent tissues lead to consider the limit as the thickness of the membrane approaches zero. We are interested in recovering the effective interface problem and the transmission conditions on the limiting zero-thickness surface, formally derived by Chaplain et al. (2019), which are compatible with nonlinear generalized Kedem-Katchalsky ones. Our analysis relies on a priori estimates and compactness arguments as well as on the construction of a suitable extension operator which allows to deal with the degeneracy of the mobility rate in the membrane, as its thickness tends to zero.
A priori estimates in context of PDEs (35B45) Reaction-diffusion equations (35K57) Degenerate parabolic equations (35K65) PDEs in connection with biology, chemistry and other natural sciences (35Q92) Existence, uniqueness, and regularity theory for compressible fluids and gas dynamics (76N10) Flows in porous media; filtration; seepage (76S05)
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