An order restricted multi-arm multi-stage clinical trial design

DOI10.1002/SIM.9314MaRDI QIDQ6628045zbMATH OpenFDO

Authors Alessandra Serra, Pavel Mozgunov, Thomas Jaki

Publication date 29 October 2024

Published in Statistics in Medicine (Search for Journal in Brave)

Copyright license Creative Commons Attribution 4.0 International

zbMATH Keywords

adaptive designsinfectious diseasesorder restrictionmulti-arm multi-stage

Mathematics Subject Classification ID

Applications of statistics to biology and medical sciences; meta analysis (62P10)

Cites work

• scientific article; zbMATH DE number 1348603 (Why is no real title available?)
• A Multiple Comparison Procedure for Comparing Several Treatments with a Control
• A gatekeeping procedure to test a primary and a secondary endpoint in a group sequential design with multiple interim looks
• A generalized Dunnett test for multi-arm multi-stage clinical studies with treatment selection
• Testing a Primary and a Secondary Endpoint in a Group Sequential Design

Cited in

(3)

• A multi-arm multi-stage platform design that allows preplanned addition of arms while still controlling the family-wise error
• A Bayesian multi-arm multi-stage clinical trial design incorporating information about treatment ordering
• Fully order restricted multi-arm multi-stage clinical trial design

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