Optimal design of cluster randomized trials allowing unequal allocation of clusters and unequal cluster size between arms

DOI10.1002/SIM.9135MaRDI QIDQ6628232zbMATH OpenFDO

Authors Andrew J. Copas, Richard Hooper

Publication date 29 October 2024

Published in Statistics in Medicine (Search for Journal in Brave)

Copyright license Creative Commons Attribution 4.0 International

Full work available at URL https://doi.org/10.1002/SIM.9135

zbMATH Keywords

cluster randomized trialoptimal designpowersample sizeunequal allocation

Mathematics Subject Classification ID

Applications of statistics to biology and medical sciences; meta analysis (62P10)

Cited in

(3)

• Sample size considerations for assessing treatment effect heterogeneity in randomized trials with heterogeneous intracluster correlations and variances
• Evaluating analytic models for individually randomized group treatment trials with complex clustering in nested and crossed designs
• How should parallel cluster randomized trials with a baseline period be analyzed? A survey of estimands and common estimators

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