A copula-based set-variant association test for bivariate continuous, binary or mixed phenotypes

DOI10.1515/IJB-2022-0010MaRDI QIDQ6636239FDOQ6636239

Authors: Julien St-Pierre, Karim Oualkacha 

Publication date: 12 November 2024

Published in: The International Journal of Biostatistics (Search for Journal in Brave)

zbMATH Keywords

generalized linear mixed modelscopulasstatistical geneticsvariance component score testgene-based testsmixed binary-continuous phenotypes

Mathematics Subject Classification ID

Applications of statistics to biology and medical sciences; meta analysis (62P10)

Cites Work

• Algorithm AS 155: The Distribution of a Linear Combination of χ 2 Random Variables
• A Geometric Perspective on the Power of Principal Component Association Tests in Multiple Phenotype Studies
• Dependence modeling with copulas
• Variance component testing in generalised linear models with random effects
• The moments of products of quadratic forms in normal variables
• Inverses of \(2\times 2\) block matrices
• Methods for analyzing multivariate phenotypes in genetic association studies
• Multivariate association test for rare variants controlling for cryptic and family relatedness

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