`Closing the loop' in biological systems modeling -- from the in silico to the in vitro

DOI10.1016/J.AUTOMATICA.2011.01.013MaRDI QIDQ665141zbMATH OpenOpenAlexWikidataFDO

Authors Alexandros Kiparissides, Michalis Koutinas, Cleo Kontoravdi, Athanasios Mantalaris, Efstratios N. Pistikopoulos

Publication date 5 March 2012

Published in Automatica (Search for Journal in Brave)

Full work available at URL https://doi.org/10.1016/j.automatica.2011.01.013

zbMATH Keywords

sensitivity analysisdesign of experimentsbiological systems model developmentmodel analysis

Mathematics Subject Classification ID

Systems biology, networks (92C42) Feedback control (93B52)

Recommendations

• scientific article; zbMATH DE number 2144776
• An approach to the creation of formal models of the influence of environmental impact on the development of biological systems
• Systems biology towards life in silico: Mathematics of the control of living cells
• scientific article; zbMATH DE number 4064807
• Control theory and systems biology.

Cites work

• scientific article; zbMATH DE number 4049588 (Why is no real title available?)
• Global sensitivity indices for nonlinear mathematical models and their Monte Carlo estimates
• Nonparametric Estimation and Sensitivity Analysis of Expected Shortfall
• On global identifiability for arbitrary model parametrizations
• On the identifiability and distinguishability of nonlinear parametric models

Cited in

(3)

• scientific article; zbMATH DE number 2144776 (Why is no real title available?)
• Global sensitivity analysis of a mathematical model of acute inflammation identifies nonlinear dependence of cumulative tissue damage on host interleukin-6 responses
• Merging on-chip and in-silico modelling for improved understanding of complex biological systems

Describes a project that uses

Uses Software

• gPROMS

This page was built for publication: `Closing the loop' in biological systems modeling -- from the in silico to the in vitro

Report a bug (only for logged in users!)Click here to report a bug for this page (MaRDI item Q665141)