`Closing the loop' in biological systems modeling -- from the in silico to the in vitro

DOI10.1016/J.AUTOMATICA.2011.01.013zbMATH Open1235.93105OpenAlexW1966293504WikidataQ62030526 ScholiaQ62030526MaRDI QIDQ665141FDOQ665141

Michalis Koutinas, Athanasios Mantalaris, Alexandros Kiparissides, Cleo Kontoravdi, Efstratios N. Pistikopoulos

Publication date: 5 March 2012

Published in: Automatica (Search for Journal in Brave)

Full work available at URL: https://doi.org/10.1016/j.automatica.2011.01.013

zbMATH Keywords

sensitivity analysisdesign of experimentsbiological systems model developmentmodel analysis

Mathematics Subject Classification ID

Systems biology, networks (92C42) Feedback control (93B52)

Cites Work

• On global identifiability for arbitrary model parametrizations
• Global sensitivity indices for nonlinear mathematical models and their Monte Carlo estimates
• On the identifiability and distinguishability of nonlinear parametric models
• Nonparametric Estimation and Sensitivity Analysis of Expected Shortfall
• Title not available (Why is that?)

Cited In (2)

• Title not available (Why is that?)
• Global sensitivity analysis of a mathematical model of acute inflammation identifies nonlinear dependence of cumulative tissue damage on host interleukin-6 responses

Uses Software

• gPROMS

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