Misinterpretation risks of global stochastic optimisation of kinetic models revealed by multiple optimisation runs

DOI10.1016/J.MBS.2018.11.002MaRDI QIDQ669142zbMATH OpenOpenAlexWikidataFDO

Authors Egils Stalidzans, Katrina Landmane, Jurijs Sulins, Sven Sahle

Publication date 20 March 2019

Published in Mathematical Biosciences (Search for Journal in Brave)

Full work available at URL https://doi.org/10.1016/j.mbs.2018.11.002

zbMATH Keywords

optimisationcopasihomeostatic constraintmetabolic engineeringparallel optimisation runs

Mathematics Subject Classification ID

Systems biology, networks (92C42) Applications of optimal control and differential games (49N90) Kinetics in biochemical problems (pharmacokinetics, enzyme kinetics, etc.) (92C45)

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• PottersWheel
• SpaceScanner
• ConvAn
• BioModels
• COPASI
• sbtoolbox

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