Misinterpretation risks of global stochastic optimisation of kinetic models revealed by multiple optimisation runs

DOI10.1016/j.mbs.2018.11.002zbMath1409.92107WikidataQ58585370 ScholiaQ58585370MaRDI QIDQ669142

Egils Stalidzans, Katrina Landmane, Jurijs Sulins, Sven Sahle

Publication date: 20 March 2019

Published in: Mathematical Biosciences (Search for Journal in Brave)

Full work available at URL: https://doi.org/10.1016/j.mbs.2018.11.002

zbMATH Keywords

metabolic engineering; optimisation; copasi; homeostatic constraint; parallel optimisation runs

Mathematics Subject Classification ID

49N90: Applications of optimal control and differential games

92C45: Kinetics in biochemical problems (pharmacokinetics, enzyme kinetics, etc.)

92C42: Systems biology, networks

Uses Software

• sbtoolbox
• COPASI
• BioModels
• ConvAn
• SpaceScanner
• PottersWheel