A systematic approach for doing an a priori identifiability study of dynamical nonlinear models

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Publication:669172

DOI10.1016/J.MBS.2018.12.012zbMATH Open1410.93034arXiv1510.06997OpenAlexW2963741434WikidataQ90615312 ScholiaQ90615312MaRDI QIDQ669172FDOQ669172


Authors: Nathalie Verdière, Sébastien Orange Edit this on Wikidata


Publication date: 20 March 2019

Published in: Mathematical Biosciences (Search for Journal in Brave)

Abstract: This paper presents a method for investigating, through an automatic procedure, the (lack of) identifiability of parametrized dynamical models. This method takes into account constraints on parameters and returns parameters whose estimations make the model identifiable. It is based on i) an equivalence between an extension of the notion of identifiability and the existence of solutions of algebraic systems, ii) the use of symbolic computations for testing their existence. This method is described in details and is applied to two examples, of which the last one involves 12 parameters.


Full work available at URL: https://arxiv.org/abs/1510.06997




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