Optimized sgRNA design to maximize activity and minimize off-target effects of CRISPR-Cas9

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DOI10.1038/NBT.3437MaRDI QIDQ68752WikidataFDO

Authors Nicolo Fusi, Meagan E Sullender, Jennifer Listgarten, John G Doench, Mudra Hegde, Emma W Vaimberg, Katherine F Donovan, Ian Smith, Zuzana Tothova, Craig Wilen, Robert Orchard, Herbert W Virgin, David E Root

Publication date 18 January 2016

Published in Nature Biotechnology (Search for Journal in Brave)

Full work available at URL https://doi.org/10.1038/NBT.3437








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