Well-posedness and asymptotic behavior a multidimensional model of morphogen transport

DOI10.1007/S00028-012-0135-5MaRDI QIDQ692815zbMATH OpenOpenAlexFDO

Authors Marcin Małogrosz

Publication date 6 December 2012

Published in Journal of Evolution Equations (Search for Journal in Brave)

Copyright license Creative Commons Attribution-NonCommercial 4.0 International

Full work available at URL https://arxiv.org/abs/1112.5833

zbMATH Keywords

initial-boundary value problembootstrap argumentsemigroup estimatesPDE-ODE system

Mathematics Subject Classification ID

Asymptotic behavior of solutions to PDEs (35B40) PDEs in connection with biology, chemistry and other natural sciences (35Q92)

Abstract: Morphogen transport is a biological process, occurring in the tissue of living organisms, which is a determining step in cell differentiation. We present rigorous analysis of a simple model of this process, which is a system coupling parabolic PDE with ODE. We prove existence and uniqueness of solutions for both stationary and evolution problems. Moreover we show that the solution converges exponentially to the equilibrium in $C^{1}imes{C}^0$ topology. We prove all results for arbitrary dimension of the domain. Our results improve significantly previously known results for the same model in the case of one dimensional domain.

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Cites work

• scientific article; zbMATH DE number 4138299 (Why is no real title available?)
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• scientific article; zbMATH DE number 1497488 (Why is no real title available?)
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Cited in

(10)

• Well-posedness and asymptotic behavior of the time-dependent solution of an \(M/G/1\) queueing model
• A model of morphogen transport in the presence of glypicans. III.
• Self-regulated biological transportation structures with general entropy dissipations. I: The 1D case
• A model of morphogen transport in the presence of glypicans. II
• A model of morphogen transport in the presence of glypicans. I
• On a parabolic-ODE system of chemotaxis
• Mathematical analysis on a multidimensional model of morphogen transport with receptor synthesis
• Global and exponential stabilization of morphogenesis models with logarithmic sensitivity and linear degradation
• Analysis of a PDE model of the swelling of mitochondria accounting for spatial movement
• Well-Posedness and Convergence to the Steady State for a Model of Morphogen Transport

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