Optimal allocation of patients in titration to fixed dose trials

DOI10.1016/S0378-3758(02)00214-8MaRDI QIDQ698010zbMATH OpenOpenAlexFDO

Authors Sudhir Gupta, Murari Singh, R. Singh, Balakrishna S. Hosmane

Publication date 18 September 2002

Published in Journal of Statistical Planning and Inference (Search for Journal in Brave)

Full work available at URL https://doi.org/10.1016/s0378-3758(02)00214-8

zbMATH Keywords

Optimal allocationClinical trialDose-escalation designLog(dose)transformationTitration trial

Mathematics Subject Classification ID

Applications of statistics to biology and medical sciences; meta analysis (62P10)

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• On Testing a Set of Correlation Coefficients for Equality

Cited in

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• A new approach towards minimizing the risk of misdosing warfarin initiation doses
• Optimal designs for dose-escalation trials and individual allocations in cohorts
• Estimation of optimum sample size allocation: an illustration with body mass index for evaluating the effect of a dietetic supplement

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