Applying Adomian decomposition method to solve Burgess equation with a non-linear source

DOI10.1007/S40819-015-0100-4zbMATH Open1395.65116arXiv1606.00259OpenAlexW3101406138MaRDI QIDQ722702FDOQ722702

R. Bernal-Jaquez, O. González-Gaxiola

Publication date: 27 July 2018

Published in: International Journal of Applied and Computational Mathematics (Search for Journal in Brave)

Abstract: In the present work we consider the mathematical model that describes brain tumour growth (glioblastomas) under medical treatment. Based on the medical study presented by R. Stupp et al. (New Engl Journal of Med 352: 987-996, 2005) which evidence that, combined therapies such as, radiotherapy and chemotherapy, produces negative tumour-growth, and using the mathematical model of P. K. Burgess et al. (J Neuropath and Exp Neur 56: 704-713, 1997) as an starting point, we present a model for tumour growth under medical treatment represented by a non-linear partial differential equation that is solved using the Adomian Decomposition Method (ADM). It is also shown that the non-linear term efficiently models the effects of the combined therapies. By means of a proper use of parameters, this model could be used for calculating doses in radiotherapy and chemotherapy.

Full work available at URL: https://arxiv.org/abs/1606.00259

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zbMATH Keywords

glioblastomaAdomian polynomialsBurgess equationtemozolomide

Mathematics Subject Classification ID

Reaction-diffusion equations (35K57) PDEs in connection with biology, chemistry and other natural sciences (35Q92) Numerical methods for partial differential equations, initial value and time-dependent initial-boundary value problems (65M99)

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Cited In (5)

• A new application of conformable Laplace decomposition method for fractional Newell-Whitehead-Segel equation
• An accelerated solution for some classes of nonlinear partial differential equations
• Title not available (Why is that?)
• NUMERICAL ASSESSMENT OF THE BRAIN TUMOR GROWTH MODEL VIA FIBONACCI AND HAAR WAVELETS
• Recent development of Adomian decomposition method for ordinary and partial differential equations

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