Regularization of ill-posed point neuron models

DOI10.1186/S13408-017-0049-1zbMATH Open1395.92044arXiv1703.00339OpenAlexW2593919153WikidataQ41010669 ScholiaQ41010669MaRDI QIDQ723665FDOQ723665

Authors: Bjørn Fredrik Nielsen 

Publication date: 24 July 2018

Published in: The Journal of Mathematical Neuroscience (Search for Journal in Brave)

Abstract: Point neuron models with a Heaviside firing rate function can be ill-posed. That is, the initial-condition-to-solution map might become discontinuous in finite time. If a Lipschitz continuous, but steep, firing rate function is employed, then standard ODE theory implies that such models are well-posed and can thus, approximately, be solved with finite precision arithmetic. We investigate whether the solution of this well-posed model converges to a solution of the ill-posed limit problem as the steepness parameter, of the firing rate function, tends to infinity. Our argument employs the Arzel`{a}-Ascoli theorem and also yields the existence of a solution of the limit problem. However, we only obtain convergence of a subsequence of the regularized solutions. This is consistent with the fact that we show that models with a Heaviside firing rate function can have several solutions. Our analysis assumes that the Lebesgue measure of the time the limit function, provided by the Arzel`{a}-Ascoli theorem, equals the threshold value for firing, is zero. If this assumption does not hold, we argue that the regularized solutions may not converge to a solution of the limit problem with a Heaviside firing function.

Full work available at URL: https://arxiv.org/abs/1703.00339

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zbMATH Keywords

regularizationexistenceill-posedHeaviside firing functionpoint neuron models

Mathematics Subject Classification ID

Neural biology (92C20) Integro-partial differential equations (45K05)

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Cited In (4)

• Ill posedness of a neural field equation with Heaviside firing rate function
• Neural firing rate model with a steep firing rate function
• On inclusions arising in neural field modeling
• Ill-posed point neuron models

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