Design principles for the analysis and construction of robustly homeostatic biological networks

DOI10.1016/J.JTBI.2016.06.036MaRDI QIDQ727167zbMATH OpenOpenAlexWikidataFDO

Authors Zhe F. Tang, David McMillen

Publication date 6 December 2016

Published in Journal of Theoretical Biology (Search for Journal in Brave)

Full work available at URL https://doi.org/10.1016/j.jtbi.2016.06.036

zbMATH Keywords

integral controlregulatory networksperfect adaptationsynthetic biologybiological regulation

Mathematics Subject Classification ID

Systems biology, networks (92C42) General biology and biomathematics (92B05)

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Cites work

• Considerations for using integral feedback control to construct a perfectly adapting synthetic gene network

Cited in

(19)

• Analysis and application of biological robustness as performance index in microbial fermentation
• Classification of infinitesimal homeostasis in four-node input-output networks
• Homeostasis in networks with multiple inputs
• Homeostasis in networks with multiple input nodes and robustness in bacterial chemotaxis
• Positive stability analysis and bio-circuit design for nonlinear biochemical networks
• The effect of integral control in oscillatory and chaotic reaction kinetic networks
• Homeostasis patterns
• Analysis of homeostatic mechanisms in biochemical networks
• Homeostasis in a feed forward loop gene regulatory motif
• The structure of infinitesimal homeostasis in input-output networks
• Design principles for perfect adaptation in biological networks with nonlinear dynamics
• Design principles for robust biochemical reaction networks: what works, what cannot work, and what might almost work
• Infinitesimal homeostasis in three-node input-output networks
• Sensitivity minimization, biological homeostasis and information theory
• Uncovering the design principles of circadian clocks: mathematical analysis of flexibility and evolutionary goals
• On biological networks capable of robust adaptation in the presence of uncertainties: a linear systems-theoretic approach
• Reverse allostasis in biological systems: minimal conditions and implications
• Homeostasis and injectivity: a reaction network perspective
• Input-output networks, singularity theory, and homeostasis

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