Sufficient conditions of endemic threshold on metapopulation networks

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Publication:739201

DOI10.1016/J.JTBI.2015.05.024zbMATH Open1343.92520arXiv1410.5116OpenAlexW2129351808WikidataQ41189017 ScholiaQ41189017MaRDI QIDQ739201FDOQ739201


Authors: Taro Takaguchi, Renaud Lambiotte Edit this on Wikidata


Publication date: 18 August 2016

Published in: Journal of Theoretical Biology (Search for Journal in Brave)

Abstract: In this paper, we focus on susceptible-infected-susceptible dynamics on metapopulation networks, where nodes represent subpopulations, and where agents diffuse and interact. Recent studies suggest that heterogeneous network structure between elements plays an important role in determining the threshold of infection rate at the onset of epidemics, a fundamental quantity governing the epidemic dynamics. We consider the general case in which the infection rate at each node depends on its population size, as shown in recent empirical observations. We first prove that a sufficient condition for the endemic threshold (i.e., its upper bound), previously derived based on a mean-field approximation of network structure, also holds true for arbitrary networks. We also derive an improved condition showing that networks with the rich-club property (i.e., high connectivity between nodes with a large number of links) are more prone to disease spreading. The dependency of infection rate on population size introduces a considerable difference between this upper bound and estimates based on mean-field approximations, even when degree-degree correlations are considered. We verify the theoretical results with numerical simulations.


Full work available at URL: https://arxiv.org/abs/1410.5116




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