Timescale analysis of a mathematical model of acetaminophen metabolism and toxicity

DOI10.1016/J.JTBI.2015.08.021zbMATH Open1343.92198OpenAlexW1496980963WikidataQ50858024 ScholiaQ50858024MaRDI QIDQ739799FDOQ739799

D. Kharzeev

Publication date: 19 August 2016

Published in: Journal of Theoretical Biology (Search for Journal in Brave)

Full work available at URL: https://doi.org/10.1016/j.jtbi.2015.08.021

zbMATH Keywords

modellingmetabolismanalysistoxicologyacetaminophen

Mathematics Subject Classification ID

Medical applications (general) (92C50) Kinetics in biochemical problems (pharmacokinetics, enzyme kinetics, etc.) (92C45)

Cites Work

• Title not available (Why is that?)
• The role of skeletal muscle in liver glutathione metabolism during acetaminophen overdose

Cited In (7)

• Use of mathematical modeling for estimation of the toxic action of some medical agents
• Predicting tyrosinaemia: a mathematical model of 4-hydroxyphenylpyruvate dioxygenase inhibition by nitisinone in rats
• Algorithmic reduction of biological networks with multiple time scales
• The role of alcohol consumption on acetaminophen induced liver injury: implications from a mathematical model
• Impulsive differential equation model in methanol poisoning detoxification. Efficacy of activated charcoal antidote in combating methanol poisoning
• Mathematical modelling of a liver hollow fibre bioreactor
• SimLivA-modeling ischemia-reperfusion injury in the liver: a first step towards a clinical decision support tool

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