A physiologically-based pharmacokinetic model for the antibiotic ertapenem

DOI10.3934/MBE.2016.13.119zbMATH1326.92031OpenAlexW2470140255WikidataQ40098289MaRDI QIDQ746554FDOQ746554

Authors Michele L. Joyner, Cammey C. Manning, Whitney Forbes, Michelle Maiden, Ariel N. Nikas

Publication date 16 October 2015

Published in Mathematical Biosciences and Engineering (Search for Journal in Brave)

Full work available at URL https://doi.org/10.3934/mbe.2016.13.119

zbMATH Keywords

ordinary differential equationsphysiologically based pharmacokinetic modelbound concentrationertapenemfree concentration

Mathematics Subject Classification ID

Kinetics in biochemical problems (pharmacokinetics, enzyme kinetics, etc.) (92C45) Numerical solution of inverse problems involving ordinary differential equations (65L09) Ordinary differential equations of infinite order (34A35)

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Cites work

• Modeling and inverse problems in the presence of uncertainty

Cited in

(1)

• Modeling Ertapenem: the impact of body mass index on distribution of the antibiotic in the body

Describes a project that uses

Uses Software

• Matlab
• DAISY

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