A mathematical model of the effects of drug resistance in cancer chemotherapy

DOI10.1016/0025-5564(84)90061-0zbMATH Open0556.92005OpenAlexW1978450356MaRDI QIDQ762091FDOQ762091

Authors: B. G. Birkhead, W. M. Gregory 

Publication date: 1984

Published in: Mathematical Biosciences (Search for Journal in Brave)

Full work available at URL: https://doi.org/10.1016/0025-5564(84)90061-0

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zbMATH Keywords

cancer chemotherapyphenotypic drug resistancecompeting treatment strategiescytotoxic agentfractional tumor reductionminimum tumor sizetumor response

Mathematics Subject Classification ID

Medical applications (general) (92C50)

Cites Work

• Tumor growth and chemotherapy: Mathematical methods, computer simulations, and experimental foundations
• Mathematical analysis of cancer chemotherapy

Cited In (22)

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• Nonlinear mathematical model of pulsed-therapy of heterogeneous tumors
• Optimization of an \textit{in vitro} chemotherapy to avoid resistant tumours
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• A mathematical model of drug resistance: Heterogeneous tumors
• The additive damage model: a mathematical model for cellular responses to drug combinations
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• A mathematical model of the P-glycoprotein pump as a mediator of multidrug resistance
• A NEW MATHEMATICAL MODELING AND SUB-OPTIMAL CHEMOTHERAPY OF CANCER
• What does not kill a tumour may make it stronger: \textit{in silico} insights into chemotherapeutic drug resistance
• A mathematical model of doxorubicin penetration through multicellular layers

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