Sensitivity analysis and identification of kinetic parameters in batch fermentation of glycerol

DOI10.1016/j.cam.2011.11.015zbMath1233.92025OpenAlexW2067777600MaRDI QIDQ765276

Jianxiong Ye, Hongchao Yin, Lei Wang, Juan Wang, En-Min Feng

Publication date: 19 March 2012

Published in: Journal of Computational and Applied Mathematics (Search for Journal in Brave)

Full work available at URL: https://doi.org/10.1016/j.cam.2011.11.015

zbMATH Keywords

parameter identificationglobal sensitivity analysisnonlinear dynamical systembatch culturegradient-based algorithm

Mathematics Subject Classification ID

Monte Carlo methods (65C05) Dynamical systems in biology (37N25) System identification (93B30) Kinetics in biochemical problems (pharmacokinetics, enzyme kinetics, etc.) (92C45) Biochemistry, molecular biology (92C40)

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Cites Work

• Complex metabolic network of glycerol fermentation by Klebsiella pneumoniae and its system identification via biological robustness
• Modeling and identification of a nonlinear hybrid dynamical system in batch fermentation of glycerol
• A computational algorithm for functional inequality constrained optimization problems
• Very fast simulated re-annealing
• Possible generalization of Boltzmann-Gibbs statistics.
• Vector measure for explicit nonlinear impulsive system of glycerol bioconversion in fed-batch cultures and its parameter identification
• A computational method for combined optimal parameter selection and optimal control problems with general constraints

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