On the influence curve for quantal bioassay

DOI10.1016/0378-3758(83)90049-6MaRDI QIDQ796242zbMATH OpenOpenAlexFDO

Authors Barry R. James, Kang Ling James

Publication date 1983

Published in Journal of Statistical Planning and Inference (Search for Journal in Brave)

Full work available at URL https://doi.org/10.1016/0378-3758(83)90049-6

zbMATH Keywords

ED 50examplesinfluence curveL-estimatorslogistic maximum likelihood estimatorM-estimatorsmedian effective dosequantal bioassayR-estimatorsrobustnesssymmetric tolerance distributiontrimmed Spearman-Kärber estimators

Mathematics Subject Classification ID

Robustness and adaptive procedures (parametric inference) (62F35) Nonparametric estimation (62G05) Applications of statistics to biology and medical sciences; meta analysis (62P10)

Review text

The concept of influence curve, as introduced by \textit{F. R. Hampel} [J. Am. Stat. Assoc. 69, 383-393 (1974; Zbl 0305.62031)], is applied and specified for ED 50 in quantal bioassay. These curves are derived for L-, M-, and R-estimators, especially for \(\alpha\)-trimmed Spearman-Kärber estimators. Their properties are demonstrated, their robustness is defined, and some examples are given.

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Cites work

• scientific article; zbMATH DE number 3386716 (Why is no real title available?)
• scientific article; zbMATH DE number 3390139 (Why is no real title available?)
• Robust estimators for quantal bioassay
• Robust Statistics
• Some Properties of the Spearman Estimator in Bioassay
• The Influence Curve and Its Role in Robust Estimation

Cited in

(1)

• On model selection for standard curve in assay development

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