Cell cycle kinetics with supramitotic control, two cell types, and unequal division: A model of transformed embryonic cells

DOI10.1016/0025-5564(91)90048-NMaRDI QIDQ808997zbMATH OpenOpenAlexWikidataFDO

Authors Marek Kimmel, Ovide Arino

Publication date 1991

Published in Mathematical Biosciences (Search for Journal in Brave)

Full work available at URL https://doi.org/10.1016/0025-5564(91)90048-n

zbMATH Keywords

asymptotic propertiesbalanced exponential growth lawcell cycle kineticsgeneration time correlationsmodel of transformed embryonic cellspedigree statisticssupramitotic regulation

Mathematics Subject Classification ID

Asymptotics of solutions to integral equations (45M05) Groups and semigroups of linear operators (47D03) Developmental biology, pattern formation (92C15)

Review text

The authors develop a mathematical model of cell kinetics with supramitotic regulation, that is, a model in which decisions controlling growth of the cell are made not at the beginning of the cell division cycle but at a previous point and their impact is extended to the next decision point, which is located in the next division cycle. The authors provide a derivation of the model based on biological information. Then they analyse the model's asymptotic properties. This is accomplished by defining an abstract semigroup of positive linear operators in an appropriate state space. Numerical calculations based on measurements are presented. The basic integral equation of the paper is the following: \[ n(t,y)=2r\int^{\infty}_{0}f(y,x)H(x-r\tau)\int n[t- (\tau +\sigma),x-r(\tau +\sigma)]d\sigma dx, \] where \(n=(n_{11},n_{12},n_{21},n_{22})\).

Recommendations

• scientific article; zbMATH DE number 67300
• scientific article; zbMATH DE number 845672
• Asymptotic Analysis of a Cell Cycle Model Based on Unequal Division
• A functional equation from cell kinetics
• Asymptotic behavior of an integral equation of cell cycle model in the light of suns and stars

Cites work

• Asymptotic Analysis of a Cell Cycle Model Based on Unequal Division
• Asymptotic behavior of a nonlinear functional-integral equation of cell kinetics with unequal division
• Asymptotic behaviour of nonlinear semigroup describing a model of selective cell growth regulation
• scientific article; zbMATH DE number 3885703 (Why is no real title available?)
• scientific article; zbMATH DE number 67300 (Why is no real title available?)
• scientific article; zbMATH DE number 3995502 (Why is no real title available?)
• scientific article; zbMATH DE number 3892029 (Why is no real title available?)
• scientific article; zbMATH DE number 3301572 (Why is no real title available?)
• One-parameter semigroups of positive operators
• Random transitions, size control, and inheritance in cell population dynamics
• Stability analysis of models of cell production systems
• The Bifurcating Autoregression Model in Cell Lineage Studies
• Theory of functional differential equations. 2nd ed
• Translation Semigroups and Their Linearizations on Spaces of Integrable Functions

Cited in

(4)

• A discrete-time, multi-type generational inheritance branching process model of cell proliferation
• Two simple models of almost the same population with very different dynamics
• Ionizing radiation damage to cells: Effects of cell cycle redistribution
• Estimation problems associated with stochastic modeling of proliferation and differentiation of O-2A progenitor cells in vitro

This page was built for publication: Cell cycle kinetics with supramitotic control, two cell types, and unequal division: A model of transformed embryonic cells

Report a bug (only for logged in users!)Click here to report a bug for this page (MaRDI item Q808997)