Which locus has the oldest allele?

DOI10.1007/BF00160191MaRDI QIDQ809924zbMATH OpenOpenAlexWikidataFDO

Authors Robert Griffiths

Publication date 1991

Published in Journal of Mathematical Biology (Search for Journal in Brave)

Full work available at URL https://doi.org/10.1007/bf00160191

zbMATH Keywords

ages of allelesalgorithmscomplete linkagedistribution of nonmutant ancestorsexpected age of the oldest allelegenealogical processindependencer-locus modeltwo-locus infinitely-many-alleles model

Mathematics Subject Classification ID

Genetics and epigenetics (92D10)

Recommendations

• The distribution of the frequencies of age-ordered alleles in a diffusion model
• Conditional ancestral times and related properties of an extant mutant at a locus A given the number of segregating sites observed at a linked locus B
• Haplotypes: the joint distribution of alleles at linked loci
• Estimating the frequency of the oldest allele: a bayesian approach
• On the two-locus sampling distribution

Cites work

• scientific article; zbMATH DE number 176645 (Why is no real title available?)
• Line-of-descent and genealogical processes, and their applications in population genetics models
• Lines of descent in the diffusion approximation of neutral Wright-Fisher models
• On the two-locus sampling distribution
• Properties of a neutral allele model with intragenic recombination
• The coalescent
• The neutral two-locus model as a measure-valued diffusion
• The transient behaviour of the Moran model in population genetics
• The use of sample genealogies for studying a selectively neutral m-loci model with recombination

Cited in

(1)

• Haplotypes: the joint distribution of alleles at linked loci

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