Mathematical analysis of a modular network coordinating the cell cycle and apoptosis

DOI10.3934/MBE.2005.2.473MaRDI QIDQ814657zbMATH OpenOpenAlexWikidataFDO

Authors Gheorghe Craciun, A. Friedman, Baltazar D. Aguda

Publication date 7 February 2006

Published in Mathematical Biosciences and Engineering (Search for Journal in Brave)

Copyright license Creative Commons Attribution 4.0 International

Full work available at URL https://doi.org/10.3934/mbe.2005.2.473

zbMATH Keywords

ordinary differential equations modelcellular processes modelsmolecular pathways

Mathematics Subject Classification ID

Medical applications (general) (92C50) Dynamical systems in biology (37N25) Cell biology (92C37)

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(5)

• Mathematical description of the interactions of CycE/Cdk2, Cdc25A, and \(\mathrm{P}27^{\mathrm{Kip}1}\) in a core cancer subnetwork
• Intracellular protein dynamics as a mathematical problem
• EQUILIBRIUM, STABILITY AND DYNAMICAL RESPONSE IN A MODEL OF THE EXTRINSIC APOPTOSIS PATHWAY
• Mathematical and computer modelling regulatory mechanisms for programmed cell death (apoptosis)
• Equilibria and stability of a class of positive feedback loops. Mathematical analysis and its application to caspase-dependent apoptosis

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