Dynamics of p53 regulatory network in DNA damage response

DOI10.1016/J.APM.2020.06.057MaRDI QIDQ821950zbMATHOpenAlexFDO

Authors Chunyan Gao, Fangqi Chen

Publication date 21 September 2021

Published in Applied Mathematical Modelling (Search for Journal in Brave)

Full work available at URL https://doi.org/10.1016/j.apm.2020.06.057

zbMATH Keywords

delaydynamicsp53 oscillationsystem parameters

Mathematics Subject Classification ID

Biochemistry, molecular biology (92C40) Qualitative investigation and simulation of models involving functional-differential equations (34K60)

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Cites work

• A Model for p53 Dynamics Triggered by DNA Damage
• On the zeros of a fourth degree exponential polynomial with applications to a neural network model with delays

Cited in

(18)

• Dynamics of posttranslational modifications of p53
• HAUSP-regulated switch from auto- to p53 ubiquitination by Mdm2 (in silico discovery)
• The role of time delays in P53 gene regulatory network stimulated by growth factor
• Modeling the roles of 14-3-3 σ and Wip1 in p53 dynamics and programmed cell death*
• Delay induced Hopf bifurcation and its control in a fractional p53 protein oscillator model
• A Model for p53 Dynamics Triggered by DNA Damage
• From structure to dynamics: frequency tuning in the p53-Mdm2 network. I: Logical approach
• Multiple time delays induced dynamics of p53 gene regulatory network
• PDCD5 functions as a regulator of p53 dynamics in the DNA damage response
• Mathematical modelling of p53 basal dynamics and DNA damage response
• Stability and bifurcation analyses of p53 gene regulatory network with time delay
• Bifurcation analysis and potential landscapes of the p53-mdm2 module regulated by the co-activator programmed cell death 5
• Oscillatory behaviors of delayed p53 regulatory network with microRNA 192 in DNA damage response
• Decision making of the p53 network: death by integration
• Synchronization in stressp53 network
• Mathematical modeling of p53 pulses in G2 phase with DNA damage
• Modeling the p53-Mdm2 dynamics triggered by DNA damage
• Cellular responding DNA damage: An improved modeling of P53 gene regulatory networks under ion radiation (IR)

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