Phenotype- and patient-specific modelling in asthma: bronchial thermoplasty and uncertainty quantification

DOI10.1016/J.JTBI.2020.110337zbMATH Open1455.92023OpenAlexW3033529396WikidataQ96225080 ScholiaQ96225080MaRDI QIDQ827872FDOQ827872

Authors: Graham M. Donovan, David Langton, Peter B. Noble 

Publication date: 13 January 2021

Published in: Journal of Theoretical Biology (Search for Journal in Brave)

Full work available at URL: https://doi.org/10.1016/j.jtbi.2020.110337

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zbMATH Keywords

airway hyper-responsivenesstargeted therapyclustered ventilation defectsventilation heterogeneity

Mathematics Subject Classification ID

Biomedical imaging and signal processing (92C55) Pathology, pathophysiology (92C32)

Cites Work

• Spatial pattern formation in the lung
• Clustered ventilation defects and bilinear respiratory reactance in asthma
• Inter-airway structural heterogeneity interacts with dynamic heterogeneity to determine lung function and flow patterns in both asthmatic and control simulated lungs
• Computational modelling of the respiratory system: discussion of coupled modelling approaches and two recent extensions

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