Asymptotics and bioavailability in a 17-compartment pharmacokinetic model with enterohepatic circulation and remetabolization

DOI10.1016/J.MBS.2006.02.001MaRDI QIDQ850104zbMATH OpenOpenAlexWikidataFDO

Authors Stefan Horkovics-Kovats, Pavol Zlatoš

Publication date 15 November 2006

Published in Mathematical Biosciences (Search for Journal in Brave)

Full work available at URL https://doi.org/10.1016/j.mbs.2006.02.001

zbMATH Keywords

identifiabilitybioavailabilityenterohepatic circulationefficiency of enterohepatic circulationremetabolizationtransition and elimination probabilities

Mathematics Subject Classification ID

Kinetics in biochemical problems (pharmacokinetics, enzyme kinetics, etc.) (92C45) Control/observation systems governed by functional relations other than differential equations (such as hybrid and switching systems) (93C30)

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Cites work

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• On the structural identifiability of biological compartmental systems in a general input-output configuration

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(2)

• scientific article; zbMATH DE number 38070 (Why is no real title available?)
• Asymptotics and bioavailability in multicompartment pharmacokinetic models with enterohepatic circulation

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