A generalized model of the repressilator

DOI10.1007/s00285-006-0035-9zbMath1113.92028OpenAlexW2099970615WikidataQ51934061 ScholiaQ51934061MaRDI QIDQ883792

Lukas Endler, Stefanie Widder, Stefan Müller, Josef Hofbauer, Peter Schuster, Christoph Flamm

Publication date: 12 June 2007

Published in: Journal of Mathematical Biology (Search for Journal in Brave)

Full work available at URL: https://doi.org/10.1007/s00285-006-0035-9

zbMATH Keywords

Hopf bifurcationStability analysisGene regulatory networkHeteroclinic cycleNegative feedback loopRepressilator

Mathematics Subject Classification ID

Kinetics in biochemical problems (pharmacokinetics, enzyme kinetics, etc.) (92C45) Biochemistry, molecular biology (92C40) Qualitative investigation and simulation of ordinary differential equation models (34C60)

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Cites Work

• The Poincaré-Bendixson theorem for monotone cyclic feedback systems
• Oscillations and multiple steady states in a cyclic gene model with repression
• Permanence and the dynamics of biological systems
• Global asymptotic stability of certain models for protein synthesis and repression
• Evolutionary Games and Population Dynamics
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