Knowledge acquisition and development of accurate rules for predicting protein stability changes

DOI10.1016/j.compbiolchem.2006.06.004zbMath1112.92023OpenAlexW2071328252WikidataQ51128821 ScholiaQ51128821MaRDI QIDQ884265

Shiow-Fen Hwang, Shinn-Ying Ho, M. Michael Gromiha, Liang-Tsung Huang

Publication date: 13 June 2007

Published in: Computational Biology and Chemistry (Search for Journal in Brave)

Full work available at URL: https://doi.org/10.1016/j.compbiolchem.2006.06.004

zbMATH Keywords

Data miningDecision treesBioinformaticsPredictionProtein stability

Mathematics Subject Classification ID

Knowledge representation (68T30) Biochemistry, molecular biology (92C40) Biophysics (92C05) Artificial intelligence (68T99) Computational methods for problems pertaining to biology (92-08)

Uses Software

• AdaBoost.MH
• C4.5

Cites Work

• A decision-theoretic generalization of on-line learning and an application to boosting
• Relative importance of secondary structure and solvent accessibility to the stability of protein mutants. A case study with amino acid properties and energetics on T4 and human lysozymes

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