A mathematical framework for understanding four-dimensional heterogeneous differentiation of \(\mathrm {CD4}^{+}\) T cells

DOI10.1007/s11538-015-0076-6zbMath1335.92025OpenAlexW1985357784WikidataQ35761513 ScholiaQ35761513MaRDI QIDQ891843

John J. Tyson, Tian Hong, Cihan Oguz

Publication date: 17 November 2015

Published in: Bulletin of Mathematical Biology (Search for Journal in Brave)

Full work available at URL: https://doi.org/10.1007/s11538-015-0076-6

zbMATH Keywords

cell differentiationimmune system\(\mathrm {CD4}^{+}\) T cells

Mathematics Subject Classification ID

Physiology (general) (92C30) Cell biology (92C37)

Related Items (3)

Controlling stochasticity in epithelial-mesenchymal transition through multiple intermediate cellular states ⋮ Modeling the dynamic behavior of biochemical regulatory networks ⋮ Fate Decisions of CD4+ T Cells

Uses Software

• PyDSTool

Cites Work

• A virtual culture of CD4+ T lymphocytes
• High-dimensional switches and the modelling of cellular differentiation
• Singularities and groups in bifurcation theory. Volume II
• Combining cytokine signalling with T-bet and GATA-3 regulation in Th1 and Th2 differentiation: a model for cellular decision-making
• Bifurcation and stability of homogeneous equilibrium configurations of an elastic body under dead-load tractions

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