Optimal experimental designs for fMRI via circulant biased weighing designs

DOI10.1214/15-AOS1352zbMATH Open1331.62381arXiv1510.08661OpenAlexW3105412187MaRDI QIDQ892250FDOQ892250

Ming-Hung Kao, Ching-Shui Cheng

Publication date: 18 November 2015

Published in: The Annals of Statistics (Search for Journal in Brave)

Abstract: Functional magnetic resonance imaging (fMRI) technology is popularly used in many fields for studying how the brain reacts to mental stimuli. The identification of optimal fMRI experimental designs is crucial for rendering precise statistical inference on brain functions, but research on this topic is very lacking. We develop a general theory to guide the selection of fMRI designs for estimating a hemodynamic response function (HRF) that models the effect over time of the mental stimulus, and for studying the comparison of two HRFs. We provide a useful connection between fMRI designs and circulant biased weighing designs, establish the statistical optimality of some well-known fMRI designs and identify several new classes of fMRI designs. Construction methods of high-quality fMRI designs are also given.

Full work available at URL: https://arxiv.org/abs/1510.08661

Recommendations

• Optimal design of fMRI experiments using circulant (almost-)orthogonal arrays
• Optimal and efficient designs for functional brain imaging experiments
• On optimal fMRI designs for correlated errors
• Efficient experimental plans for second-order event-related functional magnetic resonance imaging
• Optimization of blocked designs in fMRI studies

zbMATH Keywords

Hadamard matrixdesign efficiency\(m\)-sequencecirculant orthogonal arrayhemodynamic response function

Mathematics Subject Classification ID

Optimal statistical designs (62K05) Biomedical imaging and signal processing (92C55)

Cites Work

• On the theory of connected designs: Characterization and optimality
• General equivalence theory for optimum designs (approximate theory)
• Title not available (Why is that?)
• Orthogonal arrays. Theory and applications
• Title not available (Why is that?)
• Circulant partial Hadamard matrices
• Title not available (Why is that?)
• Title not available (Why is that?)
• On Orthogonal Matrices
• Optimality of certain asymmetrical experimental designs
• A new type of experimental designs for event-related fMRI via Hadamard matrices
• Universally optimal fMRI designs for comparing hemodynamic response functions
• On the optimality of extended maximal length linear feedback shift register sequences
• The statistical analysis of functional MRI data
• Optimality of some weighing and \(2^n\) fractional factorial designs
• D-optimum weighing designs
• Optimal repeated measurements designs: The linear optimality equations
• A-optimal weighing designs when N\(\equiv 3(mod\,4)\)
• An optimization problem with applications to optimal design theory
• On A-optimal block matrices and weighing designs when N\(\equiv 3\,(mod\,4)\)
• Title not available (Why is that?)
• Title not available (Why is that?)
• Title not available (Why is that?)

Cited In (6)

• A new type of experimental designs for event-related fMRI via Hadamard matrices
• Optimal and efficient designs for fMRI experiments via two-level circulant almost orthogonal arrays
• Title not available (Why is that?)
• Optimal and efficient designs for functional brain imaging experiments
• Efficient Designs for Event-Related Functional Magnetic Resonance Imaging with Multiple Scanning Sessions
• Recent developments in D-optimal designs

Uses Software

• FMRISTAT

This page was built for publication: Optimal experimental designs for fMRI via circulant biased weighing designs

Report a bug (only for logged in users!)Click here to report a bug for this page (MaRDI item Q892250)