Modeling the hypothalamus-pituitary-adrenal axis: A review and extension

DOI10.1016/j.mbs.2015.08.004zbMath1343.92094OpenAlexW1474235225WikidataQ28084163 ScholiaQ28084163MaRDI QIDQ897734

Andrea K. Wittenborn, Niyousha Hosseinichimeh, Hazhir Rahmandad

Publication date: 7 December 2015

Published in: Mathematical Biosciences (Search for Journal in Brave)

Full work available at URL: https://doi.org/10.1016/j.mbs.2015.08.004

zbMATH Keywords

dynamicsmathematical modelingHPA axiscircadian cyclepartial calibrationultradian cycle

Mathematics Subject Classification ID

Physiology (general) (92C30)

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Cites Work

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• Model calibration as a testing strategy for system dynamics models.
• Mathematical modeling of the hypothalamic-pituitary-adrenal gland (HPA) axis, including hippocampal mechanisms
• Mathematical modeling of the hypothalamic -- pituitary -- adrenal system activity
• Variability in the secretion of corticotropin-releasing hormone, adrenocorticotropic hormone and cortisol and understandability of the hypothalamic-pituitary-adrenal axis dynamics--a mathematical study based on clinical evidence
• Unanticipated Side Effects of Successful Quality Programs: Exploring a Paradox of Organizational Improvement
• A delay-differential equation model of the feedback-controlled hypothalamus-pituitary-adrenal axis in humans