The EM algorithm in genetics, genomics and public health

DOI10.1214/08-STS270zbMATH Open1329.62282arXiv1104.1923MaRDI QIDQ906516FDOQ906516

Authors: Nan M. Laird 

Publication date: 22 January 2016

Published in: Statistical Science (Search for Journal in Brave)

Abstract: The popularity of the EM algorithm owes much to the 1977 paper by Dempster, Laird and Rubin. That paper gave the algorithm its name, identified the general form and some key properties of the algorithm and established its broad applicability in scientific research. This review gives a nontechnical introduction to the algorithm for a general scientific audience, and presents a few examples characteristic of its application.

Full work available at URL: https://arxiv.org/abs/1104.1923

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zbMATH Keywords

maximum likelihoodincomplete datalinkage analysisdiffusion batteriesfinding regulatory motifsgene countingparticle size distributions

Mathematics Subject Classification ID

Point estimation (62F10) Classification and discrimination; cluster analysis (statistical aspects) (62H30) Applications of statistics to biology and medical sciences; meta analysis (62P10) Medical applications (general) (92C50) Genetics and epigenetics (92D10) Research exposition (monographs, survey articles) pertaining to statistics (62-02) History of mathematics in the 20th century (01A60) History of statistics (62-03)

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Cited In (5)

• Robust high dimensional expectation maximization algorithm via trimmed hard thresholding
• Title not available (Why is that?)
• The EM algorithm and the rise of computational biology
• Title not available (Why is that?)
• Title not available (Why is that?)

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