A Bayesian dose-finding design for drug combination trials with delayed toxicities
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Bayesian inference (62F15) Applications of statistics to biology and medical sciences; meta analysis (62P10) Medical applications (general) (92C50) Sampling theory, sample surveys (62D05) Optimal statistical designs (62K05) Sequential statistical design (62L05) Robustness and adaptive procedures (parametric inference) (62F35)
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- scientific article; zbMATH DE number 1154647
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(13)- Adaptive designs for drug combination informed by longitudinal model for the response
- A Bayesian adaptive design for addressing correlated late-onset outcomes in phase I/II randomized trials of drug combinations in oncology
- Constructing Release Targets for Drug Products: A Bayesian Decision Theory Approach
- A combined proof of concept and dose finding study with multiple endpoints: A Bayesian adaptive design in chronic prostatitis/chronic pelvic pain syndrome
- Adaptive Bayesian phase I clinical trial designs for estimating the maximum tolerated doses for two drugs while fully utilizing all toxicity information
- Flexible use of copula‐type model for dose‐finding in drug combination clinical trials
- Implementation of a Bayesian Design in a Dose‐Escalation Study of an Experimental Agent in Healthy Volunteers
- Evaluation of phase I clinical trial designs for combinational agents along with guidance based on simulation studies
- Bayesian dose finding for combined drugs with discrete and continuous doses
- Statistical frameworks for oncology dose-finding designs with late-onset toxicities: a review
- Application of gamma process to two-agent combinations with delayed toxicity
- Bayesian data augmentation dose finding with continual reassessment method and delayed toxicity
- Bootstrap aggregating continual reassessment method for dose finding in drug-combination trials
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